Author: Jason Vanatta, MD

University of Louisville

1.  Understand the risk for donor-transmitted malignancies to potential recipients.
2.  Develop an approach to guide decisions regarding a particular donor and to frame the discussion with potential recipients
3.  Recognize the options for treatment in the event that a transmission event is encountered
4.  Understand the regulatory requirements for an identified event

Author: Colleen Satarino, LMSW

Learning Objectives: 

1. Review the psychosocial assessment as defined in the Center for Medicare and Medicaid Services (CMS) conditions of participation

2. Consider the impact of social determinants of health regarding access to medical care and transplantation

3. Review the financial aspects of transplant for the patient

4. Discuss cases to describe the process for addressing the psychosocial and financial aspects of pre and post transplant care.

Learning Objectives:
1.  Demonstrate ability to interpret hepatitis B virus serologies and molecular testing to inform post-transplant clinical care 
2.  Understand the risks of hepatitis B virus transmission from seropositive donors and strategies for prevention of disease transmission
3.  Understand the preventive and treatment strategies for hepatitis B infection in liver transplant recipients with known infection

Author:  Kevin Gregg, MD

Co-Author: Zoe Raglow, MD

Author: Eva A. Piessens, MD, MPH

1. Understand the risk factors, prophylactic and treatment strategies, and post transplant manifestations of CMV reactivation and disease.  
2. Understand the risk factors, prophylactic and treatment strategies, and post transplant manifestations of EBV as it is associated with PTLD.
3. Understand the impact of the other Herpes viruses including HSV1 and 2, Varicella zoster virus, HHV-6, HHV-7, and HHV-9.

Author: Michael G. Ison, MD, MS

Learning Objectives:

1. Background: understand what is BK virus, prevalence, viral reactivation
2. Appreciate the clinical significance of BK after kidney transplantation (prevalence, course, manifestations and effect on graft survival)
3. Algorithm for surveillance, diagnosis and stages of BK infection and BK nephritis
4. Treatment options
5. Retransplantation in patients with graft loss due to BK nephropathy

1. Identify typical opportunistic infections associated with transplantation
2. Explain the time points post-transplantation certain types of opportunistic infections are usually observed
3. State the management of immunosuppression for a transplant patient with an opportunistic infections
4. Define the association between CMV infection, acute rejection, and long-term graft outcomes

Author: Jeffrey Tessier, MD, FACP, FIDSA

Author: Jason Vanatta, MD

1.  Understand the risk for donor-transmitted malignancies to potential recipients.

2.  Develop an approach to guide decisions regarding a particular donor and to frame the discussion with potential recipients

3.  Recognize the options for treatment in the event that a transmission event is encountered

4.  Understand the regulatory requirements for an identified event

Author: Michael G. Ison, MD, MS

Learning Objectives: 

1) Identify the behavioral and medical risk factors that qualify a donor as “increased-risk of disease transmission.”

2) Describe the sensitivity of NAT testing for HIV, HBV, HCV and quantitate the risk of transmission of new infection in the setting “window-period” negative test results.

Author: Valentina Stosor, MD

Learning Objectives:

1.  Review common pathogens encountered in posttransplant CNS infections
2.  Define the clinical presentation, diagnostic features, therapies, and prognosis of the common CNS infections

Author: Valentina Stosor, MD

Learning Objectives: 

1. Review the common infectious CNS syndromes in transplant recipients
2. Outline the diagnostic approach when CNS infection is suspected
3.  Understand the differential diagnosis for infectious and non-infectious CNS disorders following transplantation