Basic Transplant Immunobiology: Rejection

Author: Allan Kirk, MD

Learning Objectives

1.  Definition of acute and chronic allograft rejection
2.  Cellular effector mechanisms of rejection 
3.  Variables influencing alloreactivity 
4.  Acellular effector mechanisms of rejection 
5. Variables influencing alloantibody reactivity 
6. Overview of complement activation
7. Mediators of intracellular communication  
8.  Co-stimulator molecules 

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