Basic Transplant Immunobiology: Basic Concepts

Author: Allan Kirk, MD

Learning Objectives

1. Describe Basic Immunology – adaptive or specific immunity
2. Describe the relationship between antigen presenting cells and cytokines released by cells of the innate immune response
3. Describe the types of antigen presenting cells and the changes that occur following exposure to antigen
4. List the subsets of T cells and describe their function
5. Describe the distribution of MHC Class I and Class I molecules on immune cells and commonly transplanted organs
6. Describe the function of MHC Class I and Class II antigens
7. Define the first, second, and third signals involved in the initiation of an effective antigen specific response

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